In combination with exercise, nutrition is an essential component of managing horses with myopathies. The optimal feeding program for an individual horse is tailored to the diagnosis of a specific underlying myopathy. The key points of this article include: Horses with exertional rhabdomyolysis caused by types 1 and 2 polysaccharide storage myopathy (PSSM1 and PSSM2-ER) […]

Coenzyme Q10 (CoQ10) is an essential component of the mitochondrial electron transfer system and a potent antioxidant. The impact of CoQ10 supplementation on mitochondrial capacities and the muscle proteome is largely unknown. This study determined the effect of CoQ10 supplementation on muscle CoQ10 concentrations, antioxidant balance, the proteome, and mitochondrial respiratory capacities. In a randomized […]

In the mitochondria, complexes I and III of the electron transport system (ETS) generate reactive oxygen species (ROS) during exercise that are reduced by antioxidants to mitigate oxidative stress. Among these antioxidants are thiol-based antioxidants such as glutathione as well as coenzyme Q10 (CoQ10), which also transports electrons from complex I and II to complex […]