Coenzyme Q10 (CoQ10) is an essential component of the mitochondrial electron transfer system and a potent antioxidant. The impact of CoQ10 supplementation on mitochondrial capacities and the muscle proteome is largely unknown. This study determined the effect of CoQ10 supplementation on muscle CoQ10 concentrations, antioxidant balance, the proteome, and mitochondrial respiratory capacities. In a randomized […]

Researchers assessed the relationship between plasma and RBC fatty acid composition and incidence and severity of squamous gastric ulcers when altered by short- or long-chain polyunsaturated fatty acid supplementation. Thirteen fit Thoroughbred horses in training were used in this study. Horses were evaluated by gastroscopy for squamous ulcer score, gastric pH, and blood fatty acid […]

Coenzyme-Q is vital for mitochondrial respiration, but the impact of coenzyme-Q supplementation on equine skeletal muscle mitochondria is unknown. Exercising Thoroughbred horses (8.7±2.2 yr) were used in a cross-over design to test the hypothesis that supplementation of highly bioavailable coenzyme-Q (Nano-Q10, Kentucky Equine Research) would improve mitochondrial metrics in the gluteus medius. Muscle samples collected […]

Racehorses are among the most elite athletes in the equine industry. However, little is known about mitochondrial adaptations to race training. To test the hypothesis that race training increases mitochondrial biogenesis and capacity, gluteus medius samples were collected from Thoroughbred horses (11 geldings, 2 mares) before and after 14 wk of early race training. Horses […]